PURE ENCAPSULATIONS - Sereniten Plus - 45 Count - NPN: 80087511 -- Unique bioactive casein peptide blend to moderate the effects of stressHelps temporarily reduce symptoms of mild mental and physical stress with a blend of Lactium®, L-theanine and vitamin DClinically studied milk-based peptide Lactium® promotes relaxation, positive mood and other stress-related effects, including healthy digestion, sleep, and cardiovascular and cognitive functionHelps maintain immune function during stress with vitamin DLactium® is a unique, clinically researched bioactive casein decapeptide (a polypeptide 10-chain amino acid alpha-1 sequence) developed to target stress-related symptoms. In one 30-day study, subjects supplemented with 150 mg Lactium® daily reported statistically significant support for multiple stress-related effects, including digestion, mood, relaxation, sleep, and cardiovascular and cognitive function. In studies where individuals or animals were exposed to mild stressors, supplementation helped moderate healthy heart rate and blood flow, as well as plasma cortisol. Cortisol is released by the adrenal glands during acute and chronic stress. In another study, Lactium® promoted the onset of sleep and healthy sleep quality, which has been associated with cognitive function and working memory. Sleep also has been tied to metabolic health, including mitochondrial function, visceral fat deposition, alterations in gut barrier function, and changes in gut microbiota. L-Theanine, a unique amino acid derived from green tea, is responsible for its characteristic taste. L-Theanine has also been discovered to be an important biologically active constituent of green tea, and its safety is supported in studies and by its long history of safe consumption in tea. Preclinical research suggests that vitamin D plays a role in promoting healthy immune biomarkers, and may be particularly important for individuals with certain genetic variations.